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Marianne J. Legato
Wednesday, 26 February 2020 / Published in Dr. Legato's Blog

Digestive Disorders

Q. I move my bowels every three days and I wonder if this is normal?

A. Although the advertisements for commercial laxatives would have you think otherwise, there is a wide range of what is normal in terms of how frequently people move their bowels. For some people, moving their bowels once or twice a day is normal. Others move their bowels only once or twice a week. You should aim for elimination at least every third day; prolonged contact of waste matter with the colon increases your chances of colon cancer.

Constipation is usually temporary and caused by changes in lifestyle or diet: frequent travelers, for example, often experience constipation because of irregular schedules, unfamiliar surroundings and foods, and time pressure. Chronic constipation can have a number of causes; your doctor can recommend a whole series of tests to decide on what the problem actually is. Thyroid malfunction, colonic inflammation, or a tumor can all cause constipation.

Some patients have impaired colonic motility; others have a weakness or malfunction of the pelvic muscles that help evacuate stool from the body. The remedies are as varied as the causes; laxatives are usually only a temporary solution. But biofeedback, pelvic muscle retraining, and even surgery can all help.

Your bowel movements should not be difficult or painful. If you have discomfort when you defecate, if there is blood in your stool, or if you have chronic diarrhea, check with your doctor.



Marianne J. Legato
Marianne J. Legato

Marianne J. Legato, MD, Ph. D. (hon. c.), FACP is an internationally renowned academic, physician, author, lecturer, and pioneer in the field of gender-specific medicine. She is a Professor Emerita of Clinical Medicine at Columbia University College of Physicians & Surgeons and an Adjunct Professor of Medicine at Johns Hopkins Medical School. Dr. Legato is also the Director of the Foundation for Gender-Specific Medicine, which she founded in 2006 as a continuation of her work with The Partnership for Gender-Specific Medicine at Columbia University. She received an honorary PhD from the University of Panama in 2015 for her work on the differences between men and women.

At its core, gender-specific medicine is the science of how normal human biology differs between men and women and how the diagnosis and treatment of disease differs as a function of gender. Dr. Legato’s discoveries and those of her colleagues have led to a personalization of medicine that assists doctors worldwide in understanding the difference in normal function of men and women and in their sex-specific experiences of the same diseases.

She began her work in gender-specific medicine by authoring the first book on women and heart disease, The Female Heart: The Truth About Women and Coronary Artery Disease, which won the Blakeslee Award of the American Heart Association in 1992. Because of this research, the cardiovascular community began to include women in clinical trials affirming the fact that the risk factors, symptoms, and treatment of the same disease can be significantly different between the sexes. Convinced that the sex-specific differences in coronary artery disease were not unique, Dr. Legato began a wide-ranging survey of all medical specialties and in 2004, published the first textbook on gender-specific medicine, The Principles of Gender-Specific Medicine. The second edition appeared in 2010 and the third edition, dedicated to explaining how gender impacts biomedical investigation in the genomic era, won the PROSE Award in Clinical Medicine from the Association of American Publishers in 2018. A fourth edition is forthcoming.

She also founded the first scientific journals publishing new studies in the field, The Journal of Gender-Specific Medicine, and a newer version, Gender Medicine, both listed in the Index Medicus of the National Library of Medicine. She has founded a third peer-reviewed, open access journal, Gender and the Genome, which focuses on the impact of biological sex on technology and its effects on human life.

Dr. Legato is the author of multiple works, including: What Women Need to Know (Simon & Schuster, 1997), Eve’s Rib (Harmony Books, 2002), Why Men Never Remember and Women Never Forget (Rodale, 2005), Why Men Die First (Palgrave, 2008), The International Society for Gender Medicine: History and Highlights (Academic Press, 2017), and most recently, The Plasticity of Sex (Academic Press, 2020). Her books have been translated into 28 languages to date.

As an internationally respected authority on gender medicine, Dr. Legato has chaired symposia and made keynote addresses to world congresses in gender-specific medicine in Berlin, Israel, Italy, Japan, Panama, South Korea, Stockholm, and Vienna. In collaboration with the Menarini Foundation, she is co-chairing a symposium on epigenetics, Sex, Gender and Epigenetics: From Molecule to Bedside, to be held in Spring 2021 in Italy. She maintains one of the only gender-specific private practice in New York City, and she has earned recognition as one of the “Top Doctors in New York.”

Tagged under: What Women Need to Know

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