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The Foundation for Gender-Specific Medicine has collaborated with the Johns Hopkins faculty for the first in a series of symposia. This symposium reviewed some of the most common illnesses and the sex-specific manifestations and treatment of these illnesses. Furthermore, this symposium aimed to inform health care professionals to learn about gender and sex-differences in the presentation, perception and management of disease. It is of great interest that the public routinely asks for physicians educated in the science of gender-specific medicine and that to date, no specific or well organized body of evidence- based practice recommendations for all the subspecialties of medicine has yet been assembled. We are planning more collaborative symposia like this one to underscore the need to increase research where gender is a significant variable and to develop and teach sex-specific strategies for the treatment of disease.