INTERNATIONAL SYMPOSIUM – “The World Writes on the Body: How the Environment Impacts the Phenotype” – Florence, Italy – May 24-25, 2018
The 21st century began with the finalization of the description of the structure of the human genome, ushering in a profound change in our understanding what makes us what we are. We now have unprecedented power to understand the mechanisms and impact of genetic activity and the factors that modulate and control its expression. We are in the process of deciphering how age, hormones and the environment all modify behavior.
This symposium was constructed to set out the most exciting and significant science in the new field of epigenetics which is concerned with the factors that collaborate to modify genetic activity and thus mold the phenotype. Our expanding appreciation of the nature and complexity of epigenetics has produced a revolution in biomedical investigation and no less importantly, in how sociologists, anthropologists and psychologists among others consider the mechanisms of how experience changes behavior, susceptibility to disease and perhaps most importantly, how epigenetic modification of genetic activity is transmitted to future generations. Hopefully, the symposium will amplify the collaboration between biomedical investigators and social scientists by describing the final common pathway that explains how the environment modifies function.
Professors Marianne J. Legato and Gillian Einstein
Presidents of the Meeting
HOW THE ENVIRONMENT IMPACTS THE PHENOTYPE – Click here to Download .pdf
Dr. Marianne Legato, Professor Emerita of Clinical Medicine at Columbia University is an internationally known academic physician, author, lecturer, and specialist in gender-specific medicine. She is founding member of the International Society for Gender Medicine and also the founder and director of The Partnership for Gender-Specific Medicine at Columbia University and its next iteration, The Foundation for Gender-Specific Medicine. These enterprises are the first collaborations between academic medicine and the private sector focused solely on gender-specific medicine: the science of how normal human biology differs between men and women and of how the diagnosis and treatment of disease differs as a function of gender and sex. Her ground breaking textbook on Gender-and Sex Specific Medicine has been published in 2017 in the 3rd edition.
She has published extensively on Gender and Sex Specific Medicine, both scientifically and for the lay public. She is also the founding editor of the journal Gender Medicine, and the Journal Gender and Genome, published for the scientific community. In 1992, Dr. Legato won the American Heart Association’s Blakeslee Award for the best book written for the lay public on cardiovascular disease. She is a practicing internist in New York City and has been listed each year in New York Magazine’s “Best Doctors” since the feature’s inception in 1993.