Scientific Publications

We are pleased to announce that a new contract has been signed for the third edition of our textbook, The Principles of Gender-Specific Medicine. We published the first overview of what was then the new science of gender-specific medicine in 2004.  The second edition was published in 2010. Since the publication of these works, gender-specific medicine has become firmly established and is the focus of basic science and clinical investigation worldwide. Rapidly expanding and novel developments in 21st century science such as the mechanisms governing genomic expression, the potential power of synthetic biology and the increasing use of engineering to augment the performance of living beings all make a new edition essential.

Principles of Gender-Specific Medicine explains how normal human biology differs between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing new research covers various conditions that occur predominantly in men, and conditions that occur predominantly in women. Among the subjects covered are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious disease.

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“The book will benefit primary care practitioners and physicians who manage chronic conditions. By bringing the information together, Legato sets the stage for the future of an exciting and rich new field…Some chapters can serve as independent monographs, and all seem to use current references and reflect a good review of the pertinent literature. Some chapters recommend sources for additional reading. In addition, authors identify gaps in the literature and offer recommendations for further investigation. These recommendations are among the best features of the textbook…We commend the editor, section editors, and chapter authors of this wonderful textbok. Principles of Gender-Specific Medicine has the potential to change the minds of those who have struggled to understand what “gender-based medicine” really means. The bottom line is that this effort has created a broad range of research opportunities and, consequently, the chance to improve treatment and disease outcomes for all: women, men, the poor, the rich, minorities and nonminorities, and, most important, children–the next generation of men and women.”
-JAMA, 2004; 292: 2921-2922

“A new field of investigation, education, and clinical practice is to be recognized by all who practice medicine…The information in this textbook can only be found in piecemeal if at all in standard medical textbooks, and we are pleased to know that there is now a text that brings this information together.”
–William H. Wehrmacher, MD and Harry Messmore, MD, Loyola University of Chicago, Stritch School of Medicine, Maywood, IL for Clin Appl Thrombosis/Hemostasis 11(4):500, 2005